What are the dangers of pufferfish toxin
34 years old
2020-05-10
Many people are poisoned by pufferfish. What harm do pufferfish toxins have?
1 Answer These messages are for reference only
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BY Mamie Doris 2020-05-10It is an aminoperhydroquinazoline type compound. It is one of the most toxic neurotoxins found in nature. It was once considered to be the most toxic non-protein toxoid in nature. The LD50 of mice injected intraperitoneally is 8μg/kg, and its toxicity is more than 1250 times higher than that of cyanide. 0.5mg can cause death. The toxin has a local stimulating effect on the intestinal tract, and it quickly acts on nerve endings and nerve centers after absorption. It can block sodium channels on nerve excitatory membranes with high selectivity and high affinity, blocking nerve conduction, resulting in nerve palsy. death.7
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