The difference between chlorpheniramine and loratadine
The two drugs chlorpheniramine and loratadine have good effects on allergic related diseases. Many people think that these two drugs have the same effect, so basically they have similar effects. In fact, they are not the same. First, their ingredients are different, and secondly, their pharmacology is different, so there is still a certain difference between the two. What are the differences between chlorpheniramine and loratadine?
I. Pall The difference between chlorpheniramine and loratadine
1. Pharmacological differences
(1) Chlorpheniramine is an antagonist that blocks receptors and can fight allergic reactions The resulting capillary dilation reduces the difficulty of breathing caused by the contraction of bronchial smooth muscle by reducing the capillary permeability.
(2) Loratadine is the second-generation antihistamine drug, belonging to the long-acting tricyclic class of histamine drugs, which can competitively inhibit histamine receptors and allergic symptoms caused by histamine .
2. Different effects
(1) The antihistamine effect of chlorpheniramine is relatively long-lasting, and can inhibit the center, which can increase the effects of anesthetics and analgesics , Mainly in the liver.
(2) The effects of loratadine and antihistamine are fast and relatively long-lasting. This product has no calming effect and no strengthening effect on ethanol. Most of it is metabolized in the liver. Liquid medicine and feces are discharged.
3. Different efficacy
(1) Chlorpheniramine can treat urticaria, eczema and neurodermatitis. For allergic dermatitis or food allergies, it can also be treated by using it.
(2) Loratadine can treat acute or chronic urticaria, as well as allergic conjunctivitis and hay fever.
Second precautions for taking chlorpheniramine and loratadine
1. Adverse reactions
These two drugs are taken after taking There may be sleepiness, thirst and sore throat. Some people experience weakness, palpitations and ecchymosis.
2. Pay attention to diet
During the use of these two medicines, it is best not to eat spicy and cold food, but also to eat some fish food carefully.
3. People with caution
It should be used with caution for patients with hypertension, diabetes and other chronic diseases.
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